2,3,4,4a,9,9a-Hexahydro-1H-carbazole 1,2,3,4-四氢咔唑

规格: 98%
CAS: 942-01-8
产品编号: H48988
MDL: MFCD00004959
品牌: INFI
Chemical Name2,3,4,4a,9,9a-Hexahydro-1H-carbazole
MDL NumberMFCD00004959
CAS Number942-01-8
EC Number213-385-7
Beilstein Registry Number20,416
PubChem Substance ID13664
Alfabeta NameTETRAHYDROCARBAZOLE H23491---,,,
Synonym 1,2,3,4-四氢咔唑
Chemical Name Translation
LabNetwork Molecule IDLN00175886
GHS Symbol
Safety Statements
  • S37/39 Wear suitable gloves and eye/face protection 穿戴适当的手套和眼睛/面保护;
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
  • S37 Wear suitable gloves 戴适当手套;
    Risk Statements
    • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
      WGK Germany2
      Precautionary statements
      • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
      • P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服,清洗后方可重新使用
      • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
      • P302+P352+P332+P313+P362+P364
      • P312 Call a POISON CENTER or doctor/physician if you feel unwell. 如果你感觉不适,呼叫解毒中心或医生/医师。
      • P332+P313
      • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
      • P305+P351+P338
      • P305+P351+P338+P337+P313
        Hazard statements
        • H315 Causes skin irritation 会刺激皮肤
        • H319 Causes serious eye irritation 严重刺激眼睛
        • H335 May cause respiratory irritation 可能导致呼吸道刺激
        • H303 May be harmfully swallowed 吞食可能有害
          Signal word
          Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
          Warnings IRRITANT
          Hazard Codes Xi
        • {ALF} Deprotonation with excess superbasic n-BuLi/KO-t-Bu to give the N,ɑ-dianion has been studied in a variety of ether solvents. Formation of substantial amounts of the ɑ-ethyl derivative was observed with Et2O and THF, and also, remarkably, with various alkyl methyl ethers; e.g. in n-BuOMe, the ɑ-ethyl product was obtained in 60% yield. The ethyl group originates from the interaction of the solvent with the strong base, confirmed by the detection of ethylene in the absence of the tetrahydrocarbazole substrate: J. Org. Chem., 60, 8334 (1995). ɑ-Ethylation also occurred with 2-ethylindole, but not with 2-methyl- or 2-isopropyl analogues.
        • {ALF} Photooxygenation with singlet oxygen, followed by reduction of the expected hydroperoxide to the allylic alcohol, is accompanied by ring contraction to a spiro ketone. The same product is formed in high yield on treatment of the spiroketone with mineral acid: J. Org. Chem., 61, 810 (1996):
        • {ALF}
        • 942-01-8 H48988 2,3,4,4a,9,9a-Hexahydro-1H-carbazole	


          Mol. FormulaC12H13N
          Mol. Weight171.24
          Melting Point117.0 to 121.0 deg-C
          Boiling Point186°C/10mmHg(lit.)